If you have a PS3 and you don't mind playing games that are a year old, I'd recommend Infamous 2. If you have PS Plus, it's a no brainer because it's free. I'd also recommend Journey, if you have patience, and it you aren't afraid of having to think about a game to get the most out of it.
Also, if you missed Enslaved, you should probably check that out. If you like strategy, X-Com all the way. If you're a shooter fan, but you want to play a game that really pushes some boundaries, check out Spec Ops: The Line. And if you're Canadian, NHL 13.
If you want to fill up bars/level things up, Borderlands 2 is popular amongst my friends. If it's a fun, memorable, genuinely delightful single-player adventure you're craving, check out Uncharted 3.
If none of those tickle your fancy... who are you? :lol